Waters xevo g2xs qtof with acuity uplc mclass hdx 3. The waters lct premier mass spectrometer is a high performance benchtop orthogonal acceleration timeofflight oatof lcms system. Ion mobility mass spectrometry from research to routine use ion mobility to enhance your analyses our range of ims instruments will instill greater confidence in all your findings and with three to choose from, we have an instrument that will be just right for you. Waters introduces xevo g2xs qtof and xevo tqs micro mass. Micromass zq mass spectrometer, alliance 2795ht, 2996 pda, wmasslynx 4. Waters software for direct sample classification by mass spec. For more than 50 years, the company has pioneered a connected portfolio of. Waters advances proteomics and lipidomics research with. Masslynx is a software package to control analytical equipment produced by waters corporation including liquid chromatography systems such as the acquity uplc series of uhplc systems and mass spectrometers such as the xevo tqs. Waters micromass qtof premier this was removed from a working lab, but the lab could not provide the computer for intellectual property and security concerns. Redefines lipidomics research capabilities with sonar, for dataindependent acquisition lipidomics analyses. A library of 193,164 msms spectra of 41,475 ions, obtained from ion trap, collision cell, and hcd orbitrap instruments.
Ion mobility is an established technique in many applications and when coupled to mass spectrometry it provides. By integrating ms with ion mobility spectrometry ims which separates molecules on the basis of size, shape and charge the technology is provided with an additional dimension of resolution. Which masslynx scns and mass spectrometers support the. The waters 3100 mass detector provides your laboratory with a fast, simple, and flexible analytical platform that enables you to rapidly screen and confirm molecular weights, effortlessly track chromatographic peaks, purify with maximum recovery, and quantitate with superior sensitivity and selectivity. Is anyone working with waters uplc and masslynx software. Waters mass spectrometer find great deals on a wide selection of test tube rack in auctions, and classified for sale ads on labx. Expandcollapse global location which masslynx scns and mass spectrometers support the acquity arc system. December 11, 2019 rechargeable lithiumion battery evaluation application notebook november 28, 2019 shimadzu new applications are now available. Genotoxic impurity analysis in pharmaceutical products. A breakthrough came in the mid1990s with the discovery that by linking electrospray ionization esi to mass spectrometry, a robust quantitative method using a tandem quadrupole mass spectrometer to measure elevation blood levels of phenylalanine and a range of other compounds that were key signatures for other inborn metabolic disorders, was. A measure of the ions collisional cross section ccs. Select series cyclic ims ion mobility mass spectrometer. Danielle moore, field applications scientist, walks you through the process of tuning your analytes on a sciex triple quad 4500 mass spectrometer, starting at compound infusion taking you all the.
Waters has played a part in the history of mass spectrometrybased newborn screening. It is often coupled to chromatographic techniques such as gasor liquid chromatography and has found widespread adoption in the fields of analytical chemistry and biochemistry where it can be used to identify and characterize small molecules and proteins. The waters acquity ultraperformance liquid chromatograph and the micromass quattro premier triple quadrupole mass spectrometer. Improvements in ion source, transfer optics, vacuum system, tof optics and electronics have resulted in an oatof instrument with unsurpassed ion transmission that gives an order of magnitude more sensitivity. To link your upgrade request with your software, you need your software support id. The waters micromass qtof micro mass spectrometer the micromass qtof micro is a high resolution oatof mass spectrometer that enables automated exact mass measurements in an easytouse benchtop instrument. Masslynx intelligently controls any waters mass spectrometry system, from sample and solvent management components to mass spectrometer and auxiliary detectors. The xseries qtof systems are your goto benchtop systems for simplified, highthroughput data acquisition and processing for standardized analyses.
Masslynx software may acquire nominal mass, exact mass, msms and exact mass ms ms data. The software allows labs with a waters xevo g2xs qtof or synapt g2si mass spectrometer with an iknife sampling device, rapid evaporative ionization mass spectrometry reims ion source and masslynx mass spectrometry software to detect food. Ab sciex qtrap 6500 mass spectrometer system coupled with waters acquity uplc iclass system. The historical role of mass spectrometry in newborn screening. Read on to discover the fascinating journey that has brought this technology to the modern age and the remarkable discoveries that have been made along the way. This is a subset of the full nist 14 ms library, containing only the msms data and search software. Masslynx mass spectrometry software the challenges of ms and ms ms analyses are often compounded by the use of several types of analytical instruments and high personnel turnover. Liveid software is for use with waters quadrupole timeofflight qtof mass spectrometers running masslynx. Recent advances in the field originating at waters manchester site include the advent of commercial travelling wave ion mobilitymass spectrometry imsms instruments. January 10, 2020 shimadzu new applications are now available. Our exclusive contracts with our clients yield a wide range of used mass spectrometers from a number of respected oems, including agilent, thermo scientific, applied biosystems, waters, perkin elmer, and many more. X500 qtof mass spectrometer systems, high performance.
The ability to separate on shape as well as mz, enabling separation of isomers. The waters qtof premier mass spectrometer is the next generation platform for the pharmaceutical, biotechnology and life science industries. I am constantly running into software problems, like mass spec not communicating with the main computer and me having to reset everything, all the way up to. Synapt xs high definition mass spectrometer youtube. For ultrasensitive trace level quantitation, this system should be paired with the waters xevo tqxs mass spectrometer. Synapt g1 high definition mass spectrometer duke gcb. Openms opensource software for mass spectrometry analysis. January 7, 2020 celebrating 50 years of ms innovation. Masslynx is a very userfriendly software that provides an adequate, fast processing of lcmsms data. We can arrange for this system to be fully refurbished, with software, installation and validation if needed.
Any customer who purchases waters products is advised that in order to use the waters software they must purchase a license and appropriate application manager directly from waters. This application can control waters mass spectrometry system, from. Waters synapt 8k gen mass spectrometer high definition, 2008, powers on. Waters novel cyclic ims and new synapt xs lead full. Donald chace at duke university, who had been experimenting with the measurement of amino acids and acylcarnitines by fast atom bombardment fab mass spectrometry. To maintain and even increase laboratory productivity, turn to waters software to simplify interaction with your ms system and retain the ability to perform advanced experiments. Wat develops and manufactures advanced analytical and material science technologies for laboratory dependent organizations. How to request a masslynx software upgrade wkb10982 waters. Mass spectrometer qtof premier howto videos for the qtof premier system. Waters qtof premier mass spectrometer conquer scientific. Micromass zq detector the zq detector is a quadrupole mass analyzer that can determine the masstocharge ratio mz of diverse analytes. Micromass zq mass spectrometer the waters micromass zq detector with an hplc system is used to determine masstocharge ratio mz for a wide range of analytes. Equipnet is the worlds leading provider of used mass spectrometers and numerous other types of preowned equipment.
Trace elemental analysis software enable quick and easy data acquisition and analysis from quadrupole icpms, icpoes, noble gas ms and isotope ratio infrared spectrometry. Mass spectrometry software thermo fisher scientific us. Timeofflight mass spectrometry waters timeofflight ms systems, featuring quantof and ms e technologies, provide the highest uplcms performance to meet the needs of challenging qualitative and quantitative applications. This b6 laboratory customer reported results of pt samples analyte benzodiazepines concentration assay indicating a higher analyte concentration than the results calculated by waters mass spectrometry software, targetlynx. For more than 50 years, the company has pioneered a connected portfolio of separations. Utility for converting between mass spectrometer file formats, e. The waters qtof premier mass spectrometer qtof lcmsms lcms, the. The reported results were exported from b6 to the customers laboratory information management system lims. The x500b qtof system is purpose built for standard biotherapeutic characterization analyses while the x500r qtof system offers robust qualitative and quantitative performance for food, environmental, and forensic.
Mass spectrometry instrumentation from waters enables you to separate compounds by mass, charge, shape, and size. As the ideal inlet for highperformance mass spectrometers, the acquity iclass plus is designed for scientists who require the highest speed, sensitivity, resolution, and gradient precision. The waters synapt g2s high definition mass spectrometry provides complete characterization of complex mixtures and molecules with unique levels of ms performance, industry leading informatics and unparalleled platform versatility. Through highefficiency twave ion mobility user can get superior separation, enhance the peak capacity, specificity and sensitivity of the. Masslynx mass spectrometry software the challenges of ms and msms analyses are often compounded by the use of several types of analytical instruments and high personnel turnover. The instrument also features a quadrupole mass filter and collision cell for msms analyses. Mass spectrometry is a scientific technique for measuring the masstocharge ratio of ions. Accordingly, waters will provide purdue university with a synapt g2si timeofflight mass spectrometer to continue to advance research applications of desi technology. If you are familiar with them and able to visit our facility you welcome to. It provides an infrastructure for the rapid development of mass spectrometry related software as well as a rich toolset built on top of it. Why tandem mass spec is essential for newborn screening. It aids in the quick routine work in the area of forensic. History of mass spectrometry in manchester british science week in honour of british science week, we are going back to our roots to explore the rich heritage of ms in manchester. Mass spectrometry software for easy lcms analysis in clinical.
Waters micromass qtof premier mass spectrometer andbio. Mass spectrometry and bioanalytics data from separation techniques that produce traces with peaks, including ms, lcms, nmr, chromatography, and electrophoresis mass spectrometry and other bioanalytical techniques are essential in biological research to identify and quantify various biomolecules, such as proteins. Masslynx ms software permits the conversion of sample data into valuable knowledge. The ab sciex qtrap 6500 is a hybrid triple quadrupolelinear ion trap mass spectrometer which enables us to perform multiple reaction monitoring mrm, neutral loss scanning nl, precursor ion scanning pis, nlpis triggered information dependent. The id is available on two stickers that shipped with the original software. Designed for leading researchers working at the limits of conventional mass spectrometery capabilities who need to further characterize and define their samples, waters synapt tm hdms tm system offers unique, enabling functionality waters synapt hdms tm system enables analysis of samples differentiated by size and shape. Mass spectrometer xevo tqxs howto videos for the xevo tqxs contact waters. Waters masslynx software complements your lcms ms system with its intuitive user interface, intelligent instrument control, and software features built around the focus of your diagnostic analysis. Masslynx ivd mass spectrometry software with targetlynx. This is a high resolution gcms instrument with electron impact ei ionization source, suitable. The waters acquity ultraperformance liquid chromatograph.
Masslynx software can acquire nominal mass, exact mass, msms and exact mass msms data. See more with increased sensitivity and robustness for challenging compounds. Waters autospec nt magnetic sector mass spectrometer coupled with hp 6890 gc. They are available on your workstation and on your mass spectrometer.
Simplify isotope ratio mass spectrometry with software that manages instrument control, data acquisition, data processing and report generation. Software for mass spectrometry and scientific applications. Achieve ultimate flexibility for deeper discovery with the synapt xs. Every new purchase of new masslynx software comes with a 12month software plan. Waters bolsters mass spectrometry imaging portfolio with. Waters corporation develops and manufactures advanced analytical and material science technologies for laboratory dependent organizations. Masslynx software increases the speed at which you can convert your sample data into valuable knowledge.
Waters masslynx software complements your lcmsms system with its intuitive user interface, intelligent instrument control, and software features built around. The food and drug administration fda released a liquid chromatographyhigh resolution mass spectrometry lchrms method for the quantitation of nnitrosodimethylamine ndma in ranitidine drug substance and drug products using the q exactive hybrid quadrupoleorbitrap mass spectrometer. These worldclass instruments allow for structural elucidation of proteins and peptides with confidence and reproducibility. To maintain and even increase laboratory productivity, turn to waters software to simplify interaction with your ms system and retain the ability to perform. Easytouse instrument controls and software features simplify interaction with your ms system and improve laboratory. Mass spectrometry the legacy of dia data independent acquisition as of 2020, waters has over two decades of involvement in introducing, developing, and commercializing modes of data independent acquisition dia, culminating in the technologies deployed in the synap xs. An lcmsms is a liquid chromatograph lc system coupled with a quadrupole mass spectrometer ms. Q exactive hybrid quadrupoleorbitrap mass spectrometer.